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March 26, 2026Endocrinology Diabetes & Metabolism2 citationsOpen Access

Implications of Genetic Elements on Type 2 Diabetes Mellitus Pathogenesis and Management

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NNNokwanda NgcoboAfrica Health Research InstituteNSNtethelelo SibiyaRhodes University

Key Points

  • The aim is to explore how genetic factors contribute to the development and management of type 2 diabetes mellitus (T2DM).
  • Review of genetic insights related to T2DM
  • Analysis of pharmacogenomics applications in diabetes care
  • Discussion on tailoring treatments based on genetic profiles
  • Genetic insights can help identify individuals at risk for T2DM.
  • Pharmacogenomics enhances glycaemic control and reduces side effects.
  • Tailored treatments improve overall quality of life for those with T2DM.

Abstract

Therefore, understanding these genetic underpinnings is critical for advancing precision medicine approaches in diabetes care, enabling tailored pharmacotherapy and optimising treatment outcomes. By integrating genetic insights into clinical decision-making, this paper highlights the potential of pharmacogenomics not only to identify populations at risk of developing T2DM but also to improve glycaemic control, reduce adverse drug reactions, and enhance patients' quality of life with T2DM.

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Cite This Study

Ngcobo et al. (2026) studied this question.

synapsesocial.com/papers/69c4cd3efdc3bde4489194fbhttps://doi.org/10.1002/edm2.70204
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