Borderline Oxacillin-resistant Staphylococcus Aureus

Borderline oxacillin-resistant Staphylococcus aureus strains show low-level resistance to oxacillin despite lacking the mecA or mecC genes commonly found in methicillin-resistant Staphylococcus aureus . This review comprehensively examines the epidemiological trends, resistance mechanisms, clinical relevance, diagnostic hurdles, infection control measures, and ongoing research surrounding those strains. As global antibiotic consumption increases, especially in high-risk regions, a clearer understanding of Borderline oxacillin-resistant Staphylococcus aureus is vital for effective treatment and containment strategies. Strengthening laboratory diagnostics, expanding surveillance coverage, and encouraging targeted research are crucial steps in addressing its impact. A comprehensive One Health approach—encompassing human, animal, and environmental health—is essential to understand and mitigate the risks associated with them fully.