PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 26, 2026Chemical Science5 citationsOpen Access

Metal complexes in medicine: structural scaffolds vs. functional centres

NMNicolás MontesdeocaJKJohannes Karges

Key Points

  • The aim is to categorize metal-based therapeutics based on their primary roles in medicine.
  • Review of existing literature on metal complexes in therapeutics.
  • Analysis of the roles of metal centres and scaffolds in biomolecular interactions.
  • Metal complexes are identified as either structural scaffolds or reactive centres.
  • Inert scaffolds facilitate biomolecule recognition without reactivity.
  • Reactive metal centres engage in dynamic functions, influencing therapeutic outcomes.

Abstract

This review categorises metal-based therapeutics by their primary role, distinguishing between complexes acting as inert structural scaffolds for biomolecule recognition and those where the metal centre drives dynamic functional reactivity.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Montesdeoca et al. (2026) studied this question.

synapsesocial.com/papers/69c4cda5fdc3bde44891a470https://doi.org/10.1039/d6sc01182a
Ask AI
Helpful
Bookmark
Share
View Full Paper