IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and usually follows a slow, chronic course. However, in rare cases, an extracapillary or crescentic variant may develop, leading to rapidly progressive renal failure. The coexistence of IgAN with malignancy, particularly breast cancer, is exceptionally uncommon but may suggest a paraneoplastic or immune-mediated link. Understanding such associations is clinically relevant, as early recognition of atypical glomerular presentations in oncology patients may improve outcomes.
ROGER ORLANDO LEON MONTESINOS (2026) studied this question.