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March 27, 2026International Journal of Gynecology & Obstetrics0 citations

Interpregnancy intervals and maternal and neonatal outcomes: A retrospective cohort study

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CSCholpon StakeevaGZGulnur ZholdoshbekovaETElif Göknur Topçu

Key Points

  • This study aims to explore how the timing between pregnancies affects maternal and neonatal health outcomes.
  • Conducted a retrospective cohort study with 6764 multiparous women.
  • Analyzed varying interpregnancy intervals from 0 to 35 months.
  • Investigated maternal, perinatal, and neonatal outcomes.
  • Used adjusted odds ratios to evaluate risks associated with different intervals.
  • Maternal morbidity was observed in 14.9% of women studied.
  • Highest risk of maternal morbidity found at interpregnancy intervals of 6-11 and 24-35 months.
  • Short interpregnancy intervals (0-5 months) strongly linked to severe anemia and preterm birth.
  • No significant risk of extreme preterm birth found at 24-35 months interval.

Abstract

Abstract Objective Despite numerous studies on the optimal timing for planning a safe pregnancy, the impact of the interval between pregnancies on birth outcomes remains debatable. The aim of this study was to determine the association between early interpregnancy intervals (IPIs) ranging from 0 to 35 months and maternal and neonatal outcomes. Methods We conducted a retrospective cohort study involving 6764 multiparous women who gave birth between January and December 2022 at two secondary‐level maternity hospitals under the Ministry of Health of the Kyrgyz Republic. We investigated IPIs (0–5, 6–11, 12–17, 18–23 control group, and 24–35 months) in relation to maternal, perinatal, and neonatal outcomes. Results Maternal morbidity affected 14.9% of all women. The highest risk of maternal morbidity was observed at IPIs of 6–11 months (adjusted odds ratio aOR 2.634; 95% confidence interval CI 1.887–3.002) and 24–35 months (aOR 2.562; 95% CI 2.129–3.459). Mothers with short IPIs had higher odds of severe anemia (0–5 months: aOR 5.615, 95% CI 1.386–22.752; 6–11 months: aOR 2.812, 95% CI 1.007–5.891). Short IPIs were associated with higher odds of preterm birth (PTB), particularly extremely PTB (0–5 months: aOR 4.968, 95% CI 2.075–15.892; 6–11 months: aOR 4.024, 95% CI 2.361–8.452). In contrast, for an IPI of 24–35 months, the risk of extreme PTB was not statistically significant (aOR 1.110; 95% CI 0.714–2.463). Conclusion Short IPIs are significantly associated with increased risks of adverse maternal and neonatal outcomes. These findings emphasize the importance of optimal birth spacing and the need for enhanced postpartum family planning services to mitigate risks such as severe anemia and PTB.

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Cite This Study

Stakeeva et al. (2026) studied this question.

synapsesocial.com/papers/69c620be15a0a509bde1950ehttps://doi.org/10.1002/ijgo.70939
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