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March 28, 2026Kidney International Reports0 citationsOpen Access

Wcn26-124 a Focused and Pregmatic Approach to Dietary Potassium Supplementation AImed at Addressing Ongoing Persistant Hypokalemia in Individuals Undergoing Maintenance Hemodialysis

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MBMohamed Wazeer Mohamed BuharyMKManar KadahFHFayez Hejaili

Key Points

  • This research aims to evaluate the effectiveness and safety of intravenous calcium gluconate supplementation in maintaining adjusted calcium levels in chronic hemodialysis patients with persistent hypokalemia.
  • Participants received 10 mL of 10% intravenous calcium gluconate after each dialysis session, three times weekly.
  • Calcium levels were monitored monthly during the six-month follow-up period.
  • A retrospective analysis was conducted on patients who met the inclusion criteria.
  • Nine patients were included in the study, all of whom maintained adjusted calcium levels above 2.2 mmol/L.
  • There were no cases of hypercalcemia reported during the follow-up period.
  • None of the participants required hospitalizations due to hypocalcemia.

Abstract

calcium dialysate concentration of 1.75 mmol/L, intravenous vitamin D supplements, and oral calcium tablets as required, to keep adjCa levels within the desired range of 2.2 to 2.6 mmol/L.In the following six months, each participant was administered a maintenance dose of 10 mL of 10% intravenous calcium gluconate after every dialysis session, three times weekly.Adjusted calcium levels were assessed in the middle of each month.Results: A total of nine patients satisfied the inclusion criteria.All participants receiving intravenous calcium-gluconate supplementation three times a week successfully maintained their pre-dialysis adjCalcium levels above 2.2 mmol/L throughout the 6-month follow-up period, with no incidence of hypercalcemia.None of the patients needed hospital admissions due to hypocalcemia.The graph below depicts the median adjusted calcium levels prior to and following the intervention. Conclusion:The short term outcome of our intervention demonstrated effectiveness and were reassuringly safe.This suggests that alternative approaches, like intradialytic IV calcium gluconate, are suitable for outpatient settings and merit further exploration within the hemodialysis population that struggles with compliance to oral therapies.This technique may also help prevent hospitalizations for intravenous calcium treatment.However, we recommend additional validation before drawing more conclusive insights about this approach.It is important to recognize that the study has specific limitations, being a retrospective analysis with a relatively small sample size.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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Cite This Study

Buhary et al. (2026) studied this question.

synapsesocial.com/papers/69c770418bbfbc51511e077ahttps://doi.org/10.1016/j.ekir.2026.105169
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1WCN26-121 A PROTOCOL-BASED INTRAVENOUS CALCIUM GLUCONATE THERAPY IN AN OUTPATIENT ENVIRONMENT FOR CHRONIC HYPOCALCAEMIA ASSOCIATED WITH PARATHYROIDECTOMY IN PATIENTS UNDERGOING HEMODIALYSIS2026
  2. 2Calcium-Free Dialysate Hemodialysis: A Simplified Approach2024 · 1 citations
  3. 3Intravenous Paricalcitol Versus Calcitriol for Secondary Hyperparathyroidism in Maintenance Hemodialysis: A Six-Month Single-Center Retrospective Cohort Study2026
  4. 4Consequences of the implementation of “K/DOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney Disease” in a population of patients on chronic hemodialysis2007
  5. 5Influence of calcium concentration in haemodialysis fluid on blood pressure control2019 · 5 citations