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March 28, 2026Kidney International Reports0 citationsOpen Access

WCN26-7163 Disease activity assessed by glomerular Gd-IgA1 deposition

MAMai AkimotoKMKazuaki MoriRARyousuke Aoki

Key Points

  • To assess the effect of hydroxychloroquine on proteinuria levels in non-Chinese patients with glomerular Gd-IgA1 deposition.
  • Single center study design
  • Evaluation of hydroxychloroquine treatment
  • Assessment of proteinuria levels at 6 months
  • Focus on non-Chinese patient population
  • 28% of patients experienced a reduction in proteinuria
  • Hydroxychloroquine was well tolerated
  • Further research needed for diverse populations

Abstract

Conclusion:In this single center study, HCQ was well tolerated and effective in lowering proteinuria at 6 months in 28% of non-Chinese patients.Further prospective research in diverse populations and evaluation of ethnicities that may benefit most from HCQ is warranted.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.

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Cite This Study

Akimoto et al. (2026) studied this question.

synapsesocial.com/papers/69c770888bbfbc51511e0a24https://doi.org/10.1016/j.ekir.2026.106288
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