PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
March 29, 2026Cureus0 citationsOpen Access

Transcatheter Interventions in Infants With Congenital Heart Disease: A Two-Year Retrospective Case Series From a Tertiary Centre in India

RPRamesh PatelGMGaurav MittalJSJai Bharat Sharma

Key Points

  • The study aims to evaluate demographics, diagnoses, procedures, complications, and 30-day outcomes of transcatheter interventions in infants with congenital heart disease.
  • Retrospective analysis of infants with congenital heart disease at a tertiary center in India.
  • 28 infants underwent transcatheter interventions from a total of 108 admitted.
  • Data collected included demographics and procedural outcomes.
  • Successful transcatheter interventions performed in 28 infants over two years.
  • Acyanotic CHD: 100% procedural success and 30-day survival in patients undergoing PDA and VSD closures.
  • Obstructive CHD: universal success with 100% 30-day survival post balloon valvotomy and coarctoplasty.
  • Cyanotic CHD: 93% success rate, with one PDA stenting failure and two arrhythmias noted, resulting in 50% 30-day survival.

Abstract

Background: Severe forms of congenital heart disease (CHD) remain a leading cause of neonatal morbidity and mortality. In recent decades, transcatheter interventions have emerged as a less invasive, repeatable, and effective alternative to surgical treatment, particularly for critically ill neonates. Objective: This retrospective study evaluates the demographic characteristics, diagnoses, procedures, complications, and 30-day outcomes of infants undergoing transcatheter interventions for CHD at Geetanjali Medical College and Hospital, Udaipur, Rajasthan, between December 2021 and November 2023. Methods: Of 108 infants admitted with CHD during the study period, 28 underwent transcatheter interventions. Patients managed surgically or medically, or whose parents declined intervention, were excluded. Results: Transcatheter interventions were successfully performed in 28 infants with CHD over two years (2021-2023). Acyanotic CHD (n = 9) included seven patent ductus arteriosus (PDA) and two ventricular septal defect (VSD) device closures (median age = 11 months, median weight = 6 kg) with 100% procedural success and 30-day survival. Patients with obstructive CHD (n = 5) underwent balloon pulmonary valvotomy and coarctoplasty (median age = 5 months, median weight = 5.6 kg), achieving universal success and 100% 30-day survival. Patients with cyanotic CHD (n = 14) received balloon atrial septostomy (n = 5), right ventricular outflow tract stenting (n = 2), and PDA stenting (n = 7) with 93% success; one PDA stenting failure occurred alongside two cases of arrhythmias, with 50% 30-day survival cumulatively. Conclusion: Transcatheter interventions are a potentially valuable modality for safe and effective definitive or bridge to definitive treatment of infants with CHD, especially in resource-limited settings. These procedures may play a vital role in bridging the gap in paediatric cardiac care.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Patel et al. (2026) studied this question.

synapsesocial.com/papers/69c8c336de0f0f753b39de07https://doi.org/10.7759/cureus.105948
Ask AI
Helpful
Bookmark
Share
View Full Paper