The midazolam autoinjector offers a meaningful advance in the treatment of status epilepticus by enabling rapid, consistent intramuscular delivery without preparation. Its design directly addresses the practical limitations of existing therapies and is likely to encourage adoption in prehospital and other time-critical settings. As emergency care increasingly prioritizes early intervention, autoinjector-based benzodiazepines are poised to play an expanding role in modern seizure-rescue strategies.
Brigo et al. (2026) studied this question.