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Synapse
March 31, 2026Neuromuscular Disorders1 citationsOpen Access

Evaluating ChatGPT’s advice and recommendations regarding exercise for people with Inclusion Body Myositis

KSKatherine SchützeRSRuby ShehathaKBKelly Beer

Key Points

  • To assess the accuracy of ChatGPT's exercise recommendations for patients with Inclusion Body Myositis.
  • Twelve physiotherapists with expertise in Inclusion Body Myositis evaluated ChatGPT's advice.
  • Participants provided ratings based on ChatGPT's clinical knowledge and accuracy in exercise prescription.
  • Focus included both antigravity and non-antigravity movement exercises.
  • ChatGPT received high ratings for safety and accuracy in prescribing exercise for Inclusion Body Myositis.
  • Accuracy decreased for exercise recommendations regarding patients without antigravity movement.
  • The findings suggest a potential role for AI in exercise guidance for rare conditions.

Abstract

Twelve physiotherapists from around the world with expertise in Inclusion Body Myositis rated ChatGPT's clinical knowledge and exercise prescription for patients with Inclusion Body Myositis. ChatGPT was safe and mostly accurate in exercise prescription for patients with Inclusion Body Myositis. ChatGPT was less accurate when prescribing exercise for patients without antigravity movement, potentially reflecting reduced availability of literature and exercises for this population. Large language models have the potential to be a key tool in exercise prescription in rare disease populations where experts are less accessible, however the clinician will always have ultimate liability for the exercise program they prescribe.

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Cite This Study

Schütze et al. (2026) studied this question.

synapsesocial.com/papers/69cb645fe6a8c024954b8ae5https://doi.org/10.1016/j.nmd.2026.106418
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Also Consider

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  3. 3Safety and efficacy of strength training in patients with sporadic inclusion body myositis1997 · 155 citations
  4. 4Electrical stimulation of excitable tissue: design of efficacious and safe protocols2005 · 2,101 citations
  5. 5Evaluation and construction of diagnostic criteria for inclusion body myositis2014 · 249 citations