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April 1, 2026Protein and Peptide Letters1 citations

Advances in Polymeric Drug Delivery Systems: From Biodegradability to Nanocarrier Technologies

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ATAbhay ThakurRSRohit SharmaSTShriyanshu Thakur

Key Points

  • The article evaluates the impact of biodegradable polymers on drug delivery technologies, focusing on their effectiveness in controlled release.
  • Review of different types of biodegradable polymers and their production methods.
  • Categorization of polymers into natural, synthetic, and biodegradable types.
  • Assessment of polymer micelles, nanoparticles, dendrimers, and hydrogels for drug delivery efficacy.
  • Description of drug release mechanisms including diffusion, degradation, and swelling.
  • Biodegradable polymers effectively manage drug release, reducing toxic reactions.
  • Controlled-release systems show improved treatment outcomes in cancer and ocular disorders.
  • Polymeric nanocarriers enhance drug targeting and solubility, particularly for hydrophobic drugs.

Abstract

Abstract: Research studies indicate that biodegradable polymers play a crucial role in effective drug delivery, helping to manage drug release and decreasing potential toxic reactions. It thoroughly reviews different types of biodegradable polymers, the ways they are produced, and how they work for releasing drugs. The article begins by outlining drug-delivery polymers and then categorizes them into natural, synthetic, and biodegradable types. Eco-friendliness and biocompatibility are crucial attributes of degradable polymers, enhancing treatment outcomes significantly. The review covers the ways to develop and design biodegradable substances and how they are used in controlled-release medicines. The study delivers detailed descriptions of how controlled drugs are released through diffusion, degradation, and swelling. Different forms of polymer micelles, nanoparticles, dendrimers, and hydrogels are used to assess whether they can boost drug delivery methods. Polymeric nanocarriers improve targeting drugs, ensure their release over a long time, and enhance the solubility of some hydrophobic drugs. They are suitable for use in various types of therapy. The review points out that biodegradable polymers play a role in drug delivery for cancer and ocular disorders. This article aims to examine and evaluate biodegradable polymers, sharing their impacts on the development of controlled-release drug delivery technologies.

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Cite This Study

Thakur et al. (2026) studied this question.

synapsesocial.com/papers/69ccb69d16edfba7beb88493https://doi.org/10.2174/0109298665407742251124044925
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