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April 1, 2026European Heart Journal Acute Cardiovascular Care0 citationsOpen Access

Point-of-care testing for pre-hospital stratification after out-of-hospital cardiac arrest: the RAPID-MIRACLE study

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MRMuhamad Abd RazakPJP. JeyaprakashMMMichael McGarvey

Key Points

  • The study aims to assess the effectiveness of pre-hospital testing for neurological outcomes after out-of-hospital cardiac arrest.
  • Evaluated the pre-hospital application of ROSC-MIRACLE2 for neurological risk assessment.
  • Compared point-of-care pH testing with the simplified pre-MIRACLE2 score.
  • Analyzed feasibility and prognostic precision of the testing methods.
  • Point-of-care pH testing improved prognostic precision for neurological outcomes.
  • The simplified pre-MIRACLE2 score was found to be more practical with similar performance.
  • Integration of these tests into care pathways may enhance patient management but needs further validation.

Abstract

In this study, pre-hospital application of ROSC-MIRACLE2 enables early neurological risk stratification following resuscitated OHCA. Point-of-care pH improves prognostic precision, but is constrained by feasibility, whilst the simplified pre-MIRACLE2 score is more practical with comparable performance. Integration into OHCA care pathways may improve patient stratification and resource utilization but requires further study.

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Cite This Study

Razak et al. (2026) studied this question.

synapsesocial.com/papers/69ccb6b416edfba7beb885a5https://doi.org/10.1093/ehjacc/zuag036
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