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April 1, 2026Cureus0 citationsOpen Access

Lipomatous Variant of Solitary Fibrous Tumor With CD34 Negativity: A Case Report

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MBMohammed BakhtiAHAnass HalouiNKNassira Karich

Key Points

  • To report a rare case of a lipomatous variant of solitary fibrous tumor with CD34 negativity.
  • Case report of a 33-year-old patient
  • Radiological examination suggested a schwannoma
  • Surgical biopsy performed
  • Immunohistochemical studies conducted for differential diagnosis
  • Tumor comprised spindle cells within mature adipose tissue
  • CD34 negativity was observed
  • Final diagnosis confirmed after differential diagnoses were ruled out

Abstract

The solitary fibrous tumor (SFT) in its lipomatous variant is very rare, with only a few cases described in the literature. It is a myofibroblastic mesenchymal tumor with intermediate behavior. We report the case of a 33-year-old patient with no notable pathological history, admitted following the incidental discovery of a dorsal mass involving the soft tissues, whose radiological examination suggested a schwannoma. The patient underwent a surgical biopsy showing a tumoral proliferation composed of spindle cells within mature adipose tissue. Immunohistochemical studies were necessary to rule out differential diagnoses before establishing the final diagnosis.

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Cite This Study

Bakhti et al. (2026) studied this question.

synapsesocial.com/papers/69cd79e15652765b073a6b42https://doi.org/10.7759/cureus.106134
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