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April 1, 2026Diagnostics0 citationsOpen Access

A Complex Case of Renal Artery Stenosis in a 3-Year-Old Patient with Neurofibromatosis Type 1 and Secondary Hypertension

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JPJakub PytlosPMPiotr MajcherPSPiotr Skrzypczyk

Key Points

  • To discuss a case of renal artery stenosis in a child with neurofibromatosis type 1 and secondary hypertension, highlighting diagnostic challenges.
  • Case report detailing patient history and symptoms
  • Use of multimodal vascular imaging for diagnosis
  • Percutaneous transluminal renal angioplasty as an intervention
  • Post-procedural assessment through Doppler ultrasound
  • Significant right renal artery stenosis identified
  • Successful treatment with angioplasty led to transient vascular fistula
  • Subsequent Doppler ultrasound indicated changes in vascular structures
  • Case emphasizes the value of imaging in pediatric hypertension

Abstract

We describe a case of a 3-year-old girl with neurofibromatosis type 1 presenting with arterial hypertension, in whom multimodal vascular imaging identified significant right renal artery stenosis. The patient was successfully treated with percutaneous transluminal renal angioplasty; however, post-procedural Doppler ultrasound revealed a transient vascular fistula. Changes in renal arterial inflow during the procedure may have temporarily altered pressure gradients, facilitating the opening of communication involving pre-existing compensatory collateral vessels. This case illustrates the diagnostic value of multimodal vascular imaging in pediatric hypertension and highlights a rare, self-limiting post-interventional vascular phenomenon.

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Cite This Study

Pytlos et al. (2026) studied this question.

synapsesocial.com/papers/69cd7b475652765b073a9359https://doi.org/10.3390/diagnostics16071047
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