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April 3, 2026New Journal of Chemistry1 citations

Stereoselective One-Pot Synthesis of Spiro-Indenoquinoxaline-Pyrrolidine Hybrids: Structural Elucidation and Biological Evaluation

SSSivakumar ShanmugamRARameshbabu AjaydevWJWilson Joy

Key Points

  • This research aims to develop a new method for synthesizing spiro-indenoquinoxaline-pyrrolidine hybrids with specific stereochemistry.
  • Introduced a four-component one-pot synthesis approach
  • Utilized stereoselective cycloaddition reactions
  • Incorporated α-aroylideneketene dithioacetals
  • Successfully synthesized a new class of spiro-indenoquinoxaline-pyrrolidine hybrids
  • Demonstrated the effectiveness of the one-pot protocol
  • Elucidated the structures of the synthesized compounds

Abstract

A concise and stereoselective four-component, one-pot protocol has been developed for the synthesis of a new class of spiro-indenoquinoxaline-pyrrolidine hybrids with α-aroylideneketene dithioacetals via 3+2 cycloaddition. This previously unexplored approach...

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Cite This Study

Shanmugam et al. (2026) studied this question.

synapsesocial.com/papers/69cf5f005a333a821460dd13https://doi.org/10.1039/d6nj00925e
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