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October 1, 1993Circulation1,085 citationsOpen Access

Effects of age and aerobic capacity on arterial stiffness in healthy adults.

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PVPeter VaitkeviciusJFJerome L. FlegJEJ.-H. Engel

Structured PICO

Does higher aerobic capacity reduce age-associated arterial stiffness in healthy adults?

P
Population
Healthy, normotensive adults aged 20 to 90 years
I
Intervention
Higher aerobic capacity (indexed by VO2max) / endurance training
C
Comparator
Lower physical conditioning status / less active age peers
O
Outcome
Arterial stiffnesssurrogate

Higher aerobic capacity is associated with reduced arterial stiffness, suggesting that physical conditioning may mitigate age-related vascular stiffening.

Abstract

Even in normotensive, rigorously screened volunteers in whom SBP increased an average of only 14% between ages 20 and 90 years, major age-associated increases of arterial stiffness occur. Higher physical conditioning status, indexed by VO2max, was associated with reduced arterial stiffness, both within this predominantly sedentary population and in endurance trained older men relative to their less active age peers. These findings suggest that interventions to improve aerobic capacity may mitigate the stiffening of the arterial tree that accompanies normative aging.

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Cite This Study

Vaitkevicius et al. (1993) studied this question.

synapsesocial.com/papers/69d07eb7632f68323204f575https://doi.org/10.1161/01.cir.88.4.1456
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