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April 5, 2026Value in Health Regional Issues0 citationsOpen Access

Healthcare Resource Utilization and Costs After Disease Progression With First-Line Systemic Therapy in Patients With Advanced Endometrial Cancer in the United States

LMLaura Moore-SchiltzSLSolomon J. LubingaJTJoseph Tkacz

Key Points

  • To investigate healthcare resource utilization (HCRU) and costs associated with disease progression following first-line systemic therapy in advanced endometrial cancer.
  • Analyzed healthcare resource utilization data post-treatment initiation
  • Assessed treatment-free interval (TFI) less than 6 months
  • Evaluated costs related to disease progression and treatment plans
  • Identified higher healthcare resource utilization correlated with shorter treatment-free intervals
  • Found significant increase in endometrial cancer-specific costs following disease progression
  • Suggested that effective upfront treatments can reduce subsequent healthcare costs

Abstract

Patients with advanced EC initiating subsequent treatment face considerable HCRU and costs. Because most patients had a <6-month TFI, which is indicative of faster disease progression and associated with numerically higher HCRU and significantly higher EC-specific costs, this study suggests that effective up-front treatments may help alleviate this burden.

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Cite This Study

Moore-Schiltz et al. (2026) studied this question.

synapsesocial.com/papers/69d1fc28a79560c99a0a1cb4https://doi.org/10.1016/j.vhri.2026.101618
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