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April 5, 2026Clinical Transplantation0 citationsOpen Access

Pancreas Transplantation in the Modern Era: Observations and Implications of Donor Pancreas Extraction Time

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MDMichael A. DealCKChristof KaltenmeierPNPerwaiz Nawabi

Key Points

  • This research aims to explore the impact of donor pancreas extraction time on transplantation outcomes.
  • Analyzed data from deceased donor pancreas transplants at a single US center.
  • Stratified patients by extraction time (ET) into two groups: ET ≤ 40 min and ET > 40 min.
  • Conducted retrospective review of transplantation outcomes, including graft loss and readmission rates.
  • No significant difference in all-cause graft loss between ET groups (6.9% vs 12%, p = 0.482).
  • Higher readmission rate at 90 days for ET ≤ 40 min group (60% vs 39%, p = 0.015).
  • Study indicates ET impacts postoperative outcomes despite no effect on graft loss.

Abstract

There has been a worldwide reduction in pancreas transplant volume over the last decade. Understanding factors, such as procurement extraction time (ET), that play a key role in organ recovery can increase confidence in organ acceptance and improve organ utilization. All patients who underwent deceased donor pancreas transplantation at a single US center between January 2019 and August 2024 were stratified by ET and retrospectively reviewed. A total of 137 transplants were included in the analysis with 72 patients in the ET ≤ 40 min group and 65 patients in the ET > 40 min group. We found no significant difference in all-cause pancreas graft loss between the ET ≤ 40 min and ET > 40 min group (6.9% vs 12%; p = 0.482), but there was a higher readmission rate at 90 days in the ET ≤ 40 min group (60% vs 39%; p = 0.015) regardless of adjustments in multivariate analysis. We demonstrate for the first time at a US center that while ET is not associated with all-cause graft loss, it may impact postoperative outcomes such as readmission rates and could have important implications for the future of pancreas utilization.

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Cite This Study

Deal et al. (2026) studied this question.

synapsesocial.com/papers/69d1fcc0a79560c99a0a260ehttps://doi.org/10.1111/ctr.70512
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