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April 5, 2026Cancer Research0 citations

Abstract 858: Patient navigation as an equity intervention in head and neck cancer: Perspectives from a geocoded EMR cohort and qualitative insights from frontline navigators.

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ALAlexandra L. LindgrenDMDiana MoralesTBTrista Beard

Key Result

Qualitative evaluation of a head and neck cancer patient navigation program demonstrated strong engagement in patient-centered interventions, with navigator composite scores ranging from 6 to 8 of 9.

Key Points

  • The study aims to evaluate the effects of patient navigation on post-operative radiation therapy (PORT) delays in head and neck cancer patients, focusing on related disparities.
  • Mixed methods approach combining quantitative dataset analysis and qualitative interviews with navigators
  • Quantitative analysis of PORT timeliness pre-and-post initiation of the Patient Navigation program
  • Multivariable regression to adjust for clinical factors and social determinants of health
  • Qualitative thematic analysis based on semi-structured interviews with navigators
  • Identified baseline disparities in PORT timeliness related to social determinants of health
  • Navigator composite scores showed strong engagement in patient-centered interventions
  • Four key themes emerged from navigator interviews: coordination, process improvement, barriers, and program growth
  • Quantitative findings will include distributions of time to PORT and factors influencing adherence

Study Design

Type

Observational

Multicenter

No

Structured PICO

Does a Patient Navigation program improve post-operative radiation therapy timeliness in head and neck cancer patients?

P
Population
Head and neck cancer patients at a tertiary academic Head and Neck surgical center, and employed Head and Neck Cancer Patient Navigators
I
Intervention
Patient Navigation HNC program
C
Comparator
Pre-initiation of the Patient Navigation HNC program
O
Outcome
PORT timeliness pre-and-post initiation of the Patient Navigation HNC program

Patient navigation in head and neck cancer involves relational coordination and process improvement, with quantitative evaluation of its impact on radiation therapy delays pending.

Abstract

Abstract Background: In head and neck cancer (HNC), shorter time from surgery to post-operative radiation therapy (PORT) is associated with survival and improved local control. However, delays are common and distributed unevenly, reflecting social determinants of health (SDOH) such as insurance, transportation, language, and housing and food instability. Patient Navigation has been demonstrated to improve screening, follow up, and appointment adherence in breast, lung, and colorectal cancers; however, rigorous evaluations specific to HNC patient navigation and PORT timelines remain extremely limited. This mixed methods study explores the lived experiences and perceived impact of navigators working within a tertiary academic Head and Neck surgical center. Methods: This concurrent mixed method study includes a quantitative arm and a quantitative interview arm. The quantitative arm utilizes a curated dataset with prespecified inclusion/exclusion criteria with the primary aim of describing baseline disparities in PORT timeliness pre-and-post initiation of the Patient Navigation HNC program and the secondary aims assessing 90-day post-operative emergency room visits and one year survival. Multivariable regression and time-to-event analysis will adjust for clinical factors and SDOH covariates. The qualitative arm comprises semi-structured interviews with all employed Head and Neck Cancer Patient Navigators (PNs). Analysis was conducted utilizing an inductive thematic approach. Interviews were then appraised using a structured three-domain evaluation framework. Results: Four overarching themes emerged from the conversations: (1) Relational coordination and patient advocacy (2) Incremental process improvement (3) Systematic Barriers and Resource Constraints (4) Vision for program growth. Navigator composite scores ranged from 6-8 of 9, reflecting strong engagement in patient-centered interventions and iterative workflow improvements. For the quantitative arm we will report (1) distributions of time to PORT across SDOH strata (2) adjusted effect estimates for PN on timeliness and adherence, and (3) themes mapping structural and process barriers to delays. Mixed methods integration will yield targets for intervention and measurable Patient Navigator performance indicators. Conclusions: By pairing robust analytics with Patient Navigator perspectives, this study will clarify if and how patient navigation reduces PORT delays in HNC, define SDOH-responsive metrics for quality improvement of Patient Navigation programs, and inform scalable implementation to improve both oncologic and equity outcomes. Citation Format: Alexandra L. Lindgren, Diana L. Morales, Trista A. Beard, Alyssa F. Harlow, Chanita Hughes Halbert. Patient navigation as an equity intervention in head and neck cancer: Perspectives from a geocoded EMR cohort and qualitative insights from frontline navigators abstract. In: Proceedings of the American Association for Cancer Research Annual Meeting 2026; Part 1 (Regular Abstracts); 2026 Apr 17-22; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2026;86(7 Suppl):Abstract nr 858.

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Cite This Study

Lindgren et al. (2026) conducted an observational in Head and neck cancer. Patient Navigation vs. Pre-initiation of Patient Navigation was evaluated on Time to post-operative radiation therapy (PORT). Qualitative evaluation of a head and neck cancer patient navigation program demonstrated strong engagement in patient-centered interventions, with navigator composite scores ranging from 6 to 8 of 9.

synapsesocial.com/papers/69d1fdb0a79560c99a0a3eb5https://doi.org/10.1158/1538-7445.am2026-858
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