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April 5, 2026Cancer Research

Abstract 1392: A mixed-methods evaluation of multilevel barriers and facilitators to inform implementation strategies for advancing equitable clinical trial accrual in a large comprehensive cancer center.

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Authors

MGMorgan GillSIS. IqbalVKVibha Kodancha

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Overview

Mixed-methods evaluation identifies barriers and facilitators to optimize trial accrual in oncology settings, highlighting implications for equitable access.

Key Points

  • This study aims to evaluate the multilevel barriers and facilitators affecting clinical trial enrollment in a cancer center.
  • Conducted mixed-methods design including surveys and interviews with oncology providers.
  • Utilized the Consolidated Framework for Implementation Research to analyze data.
  • Assessed provider experiences related to trial enrollment, including their beliefs, attitudes, and knowledge.
  • Identified key barriers and facilitators affecting trial accrual through qualitative coding of interview transcripts.
  • 96% of providers acknowledged the importance of clinical trials for patient care.
  • 45% of providers reported gaps in knowledge about trial accrual.
  • 74% of main campus providers cited limited staffing support, contrasting with 20% at satellite clinics (p=0.003).
  • 64% at the main campus and 53% at satellite clinics noted limited language resources for patients (p=0.44).
  • Provider motivation and interest in trial training were recognized as key facilitators.

Cite This Study

Gill et al. (2026) studied this question.

synapsesocial.com/papers/69d1fdf7a79560c99a0a44cehttps://doi.org/10.1158/1538-7445.am2026-1392
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Also Consider

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  1. 1Barriers to Clinical Trial Implementation Among Community Care Centers2024 · 44 citations
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  3. 3Abstract 999: Clinical trial matchmaking: Connecting sites to sponsors2024
  4. 4Perspectives of facilitators and barriers to cancer clinical trial participation: A mixed-methods study.2024 · 3 citations
  5. 5Abstract B103: Moving the needle: Values and communication strategies of clinical investigators for clinical trial recruitment2025