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April 5, 2026JACC Case Reports1 citationsOpen Access

Differentiating LAA Thrombus From Spontaneous Echo Contrast for Safe LAA Occlusion

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ASAshraf SliemSDSteven DouediCCC. L. Chen

Key Result

Adjunctive modalities successfully differentiated true thrombus from spontaneous echo contrast, allowing safe left atrial appendage occluder deployment in a series of cases.

Key Points

  • The study aims to differentiate true thrombus from spontaneous echo contrast in the left atrial appendage to ensure safe occlusion procedures.
  • Conducted a series of cases involving LAA occlusion procedures.
  • Utilized transesophageal echocardiography to assess LAA conditions.
  • Applied adjunctive modalities to enhance distinction between thrombus and echo contrast.
  • Successfully identified true thrombus and echo contrast in cases.
  • Enabled safe deployment of LAA occluders without procedural complications.

Study Design

Type

Case Report

Structured PICO

P
Population
Patients with atrial fibrillation and contraindication to long-term anticoagulation undergoing evaluation for left atrial appendage (LAA) occlusion
I
Intervention
Adjunctive imaging modalities to differentiate LAA thrombus from spontaneous echo contrast
O
Outcome
Safe LAA occluder deployment

Adjunctive imaging modalities can help differentiate true LAA thrombus from spontaneous echo contrast to safely guide LAA occlusion.

Abstract

Left atrial appendage (LAA) occlusion is a valuable therapeutic option for stroke prevention in patients with atrial fibrillation who have contraindication to long-term anticoagulation. However, the presence of LAA thrombus is a contraindication to device implantation. Differentiating a true thrombus from spontaneous echo contrast or "sludge" on transesophageal echocardiography is both challenging and crucial for procedural safety. We present a series of cases using adjunctive modalities that allowed safe LAA occluder deployment.

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Cite This Study

Sliem et al. (2026) conducted a case report in Atrial fibrillation. Adjunctive modalities was evaluated on Safe LAA occluder deployment. Adjunctive modalities successfully differentiated true thrombus from spontaneous echo contrast, allowing safe left atrial appendage occluder deployment in a series of cases.

synapsesocial.com/papers/69d1fdf7a79560c99a0a45a8https://doi.org/10.1016/j.jaccas.2026.107760
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