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April 6, 2026Alimentary Pharmacology & Therapeutics4 citations

HBsAg Quantification‐Based Models for Predicting Hepatocellular Carcinoma Risk in Nucleos(t)ide Analogs‐Experienced Patients With Chronic Hepatitis B: The HBsAg ‐ HCC Score

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YGYi‐Fan GuoXNXiao‐Xia NiuLLLe Li

Key Points

  • The research aims to improve HCC risk prediction using HBsAg quantification in patients with chronic hepatitis B who have been treated with nucleos(t)ide analogs.
  • Developed HBsAg-HCC Score incorporating HBsAg quantification
  • Focused on nucleos(t)ide analogs-experienced patients with chronic hepatitis B
  • Compared with conventional risk models to identify improvements
  • Demonstrated improved accuracy in HCC risk stratification
  • Identified HBsAg as a significant marker for predicting outcomes
  • Addressed limitations in existing risk prediction models

Abstract

By incorporating HBsAg quantification, a virus-specific marker often missing from conventional models, the HBsAg-HCC Score offers a more comprehensive and accurate approach to HCC risk stratification in NAs-experienced CHB patients, addressing a critical limitation of existing models directly.

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Cite This Study

Guo et al. (2026) studied this question.

synapsesocial.com/papers/69d34e579c07852e0af97dcchttps://doi.org/10.1111/apt.70652
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