Does urgent surgery improve efficacy or reduce complications compared to fibrinolytic therapy in patients with symptomatic left-sided prosthetic valve thrombosis?
In symptomatic left-sided prosthetic valve thrombosis, fibrinolytic therapy may offer a safer alternative to urgent surgery, avoiding higher mortality and complication risks despite a greater chance of residual valve dysfunction.
In symptomatic left-sided PVT, urgent surgery is not more efficacious than FT. Surgery is associated with a higher risk of complications, including death, while FT is more often associated with residual valve dysfunction.
Karthikeyan et al. (2025) studied this question.
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