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March 2, 2010European Heart Journal1,368 citationsOpen Access

Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis

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CVC VlachopoulosKAKonstantinos AznaouridisMOMichael F. O’Rourke

Structured PICO

Do central haemodynamic indexes predict future cardiovascular events and all-cause mortality independently of or better than peripheral pressures?

I
Intervention
Measurement of central haemodynamic indexes (augmentation index, central pulse pressure)
C
Comparator
Measurement of peripheral pressures (peripheral pulse pressure)
O
Outcome
Future cardiovascular events and all-cause mortalityhard clinical

Central haemodynamic indexes, particularly augmentation index, are independent predictors of cardiovascular events and mortality, though central pulse pressure is not significantly better than peripheral pulse pressure for risk prediction.

Abstract

Central haemodynamic indexes are independent predictors of future CV events and all-cause mortality. Augmentation index predicts clinical events independently of peripheral pressures, while central PP has a marginally but not significantly (P = 0.057) better predictive ability when compared with peripheral PP.

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Cite This Study

Vlachopoulos et al. (2010) studied this question.

synapsesocial.com/papers/69d56c1375589c71d767cb3ahttps://doi.org/10.1093/eurheartj/ehq024
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