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November 26, 2009New England Journal of Medicine903 citationsOpen Access

A Sensitive Cardiac Troponin T Assay in Stable Coronary Artery Disease

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TOTorbjørn OmlandJLJames A. de LemosMSMarc S. Sabatine

Structured PICO

Are cardiac troponin T concentrations measured with a highly sensitive assay associated with cardiovascular death, heart failure, or myocardial infarction in patients with stable coronary artery disease?

P
Population
Patients with stable coronary artery disease
I
Intervention
Highly sensitive cardiac troponin T assay (prognostic biomarker evaluation)
O
Outcome
Incidence of cardiovascular death, heart failure, and myocardial infarctionhard clinical

Highly sensitive cardiac troponin T is a significant prognostic marker for cardiovascular death and heart failure in patients with stable coronary artery disease.

Abstract

After adjustment for other independent prognostic indicators, cardiac troponin T concentrations as measured with a highly sensitive assay were significantly associated with the incidence of cardiovascular death and heart failure but not with myocardial infarction in patients with stable coronary artery disease.

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Cite This Study

Omland et al. (2009) studied this question.

synapsesocial.com/papers/69d56c2075589c71d767cbechttps://doi.org/10.1056/nejmoa0805299
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Prognostic Value of Serum Troponin T in Unstable Angina1992 · 965 citations
  2. 2Angiotensin-Converting–Enzyme Inhibition in Stable Coronary Artery Disease2004 · 1,133 citations
  3. 3Apoptosis in the Failing Human Heart1997 · 1,686 citations
  4. 4Persistent Cardiac Troponin I Elevation in Stabilized Patients After an Episode of Acute Coronary Syndrome Predicts Long-Term Mortality2007 · 157 citations
  5. 5Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure2007 · 713 citations