Age-related deterioration of left ventricular diastolic function is more pronounced in elderly females, which may contribute to their higher risk of diastolic heart failure.
Age-related changes in diastolic indices were gender specific. In the elderly population, diastolic function deteriorated more significantly in the female gender than in the male gender. These results may explain the relatively higher incidence in elderly females among patients with diastolic heart failure and higher cardiovascular mortality in the female gender.
Okura et al. (2009) studied this question.