PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
August 1, 2013European Heart Journal956 citations

Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences

View Full Paper
RCRajiv ChowdhuryHKHassan KhanEHEmma E Heydon

Key Points

  • To assess the prevalence of suboptimal adherence to cardiovascular medications and quantify its impact on adverse clinical outcomes.
  • Conducted a meta-analysis evaluating prevalence rates of adherence across various cardiovascular disease medications.
  • Performed absolute and relative risk assessments to determine the proportion of cardiovascular events attributable to poor adherence.
  • Suboptimal adherence is widespread and exhibits a similar prevalence across all individual cardiovascular disease medications.
  • Approximately 9% of all cardiovascular disease events in Europe are attributable to poor adherence to vascular medications alone.
  • Optimal adherence exhibits a significant inverse association with subsequent adverse clinical outcomes.

Abstract

A substantial proportion of people do not adhere adequately to cardiovascular medications, and the prevalence of suboptimal adherence is similar across all individual CVD medications. Absolute and relative risk assessments demonstrate that a considerable proportion of all CVD events (~9% in Europe) could be attributed to poor adherence to vascular medications alone, and that the level of optimal adherence confers a significant inverse association with subsequent adverse outcomes. Measures to enhance adherence to help maximize the potentials of effective cardiac therapies in the clinical setting are urgently required.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Chowdhury et al. (2013) studied this question.

synapsesocial.com/papers/69d56e2675589c71d767d43chttps://doi.org/10.1093/eurheartj/eht295
Ask AI
Helpful
Bookmark
Share
View Full Paper