Are elevated serum carboxymethyl-lysine (advanced glycation end products) levels associated with increased aortic pulse wave velocity in relatively healthy community-dwelling adults?
Elevated advanced glycation end products are associated with increased arterial stiffness in healthy adults, suggesting a potential target for dietary intervention to lower cardiovascular risk.
Elevated AGEs are associated with increased arterial stiffness, a known predictor of adverse cardiovascular outcomes, among relatively healthy community-dwelling adults. Interventions to lower levels of AGEs, such as altering the pattern of dietary intake, warrant examination as putative novel strategies to lower arterial stiffness in adults.
Semba et al. (2008) studied this question.