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December 15, 2004New England Journal of Medicine1,391 citationsOpen Access

Risk of Myocardial Infarction and Stroke after Acute Infection or Vaccination

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LSLiam SmeethSTSara L. ThomasAHAndrew Hall

Key Points

  • To examine the association between acute infections and the risk of myocardial infarction and stroke compared to vaccinations.
  • Analyzed data on the incidence of myocardial infarction and stroke following acute infections and vaccinations.
  • Compared outcomes between infections and vaccinations such as influenza, tetanus, and pneumococcus.
  • Acute infections are linked to a temporary increase in the risk of myocardial infarction and stroke.
  • Influenza, tetanus, and pneumococcal vaccinations do not lead to a measurable increase in the risk of vascular events.

Abstract

Our findings provide support for the concept that acute infections are associated with a transient increase in the risk of vascular events. By contrast, influenza, tetanus, and pneumococcal vaccinations do not produce a detectable increase in the risk of vascular events.

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Cite This Study

Smeeth et al. (2004) studied this question.

synapsesocial.com/papers/69d570ca75589c71d767df40https://doi.org/10.1056/nejmoa041747
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