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February 7, 2017Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials76 citationsOpen Access

Understanding the requirements of self-expandable stents for heart valve replacement: Radial force, hoop force and equilibrium

MCMaria CabreraCOC.W.J. OomensFBFrank Frank Baaijens

Structured PICO

P
Population
Experimental and computational models of a nitinol stent, including simulations of deployment against ovine and human pulmonary arteries
I
Intervention
Nitinol self-expandable stent for tissue-engineered heart valve implantation
O
Outcome
Mechanical response to parallel plate compression and radial crimping, hoop force, radial force, and equilibrium diametersurrogate

Computational and experimental models successfully characterized the radial and hoop forces of a nitinol self-expandable stent for heart valve replacement, providing insights into equilibrium diameters during deployment.

Abstract

A proper interpretation of the forces developed during stent crimping and deployment is of paramount importance for a better understanding of the requirements for successful heart valve replacement. The present study combines experimental and computational methods to assess the performance of a nitinol stent for tissue-engineered heart valve implantation. To validate the stent model, the mechanical response to parallel plate compression and radial crimping was evaluated experimentally. Finite element simulations showed good agreement with the experimental findings. The computational models were further used to determine the hoop force on the stent and radial force on a rigid tool during crimping and self-expansion. In addition, stent deployment against ovine and human pulmonary arteries was simulated to determine the hoop force on the stent-artery system and the equilibrium diameter for different degrees of oversizing.

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Cite This Study

Cabrera et al. (2017) studied this question.

synapsesocial.com/papers/69d5731c9d980f6498ccb2cdhttps://doi.org/10.1016/j.jmbbm.2017.02.006
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