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December 17, 2023Journal of Cardiovascular Electrophysiology62 citationsOpen Access

Myocardial injury and inflammation following pulsed‐field ablation and very high‐power short‐duration ablation for atrial fibrillation

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MPMiruna PopaFBFabian BahlkeMKMarc Kottmaier

Structured PICO

Does pulsed-field ablation affect myocardial injury and inflammation compared to other ablation technologies in patients with atrial fibrillation?

P
Population
Patients with atrial fibrillation
I
Intervention
Pulsed-field ablation (PFA) and very high-power short-duration ablation
C
Comparator
Other ablation technologies (four investigated in total)
O
Outcome
Myocardial injury and inflammationsurrogate

Pulsed-field ablation for atrial fibrillation causes more myocardial injury but less inflammation compared to other ablation technologies.

Abstract

Among the four investigated ablation technologies, PFA was associated with the highest myocardial injury and the lowest inflammatory reaction.

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Cite This Study

Popa et al. (2023) studied this question.

synapsesocial.com/papers/69d5733d9d980f6498ccb345https://doi.org/10.1111/jce.16157
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Irreversible electroporation ablation for atrial fibrillation2018 · 48 citations
  2. 2The Effect of Radiofrequency Catheter Ablation on Myocardial Creatine Kinase Activity1995 · 33 citations
  3. 3Safety profile and long-term efficacy of very high-power short-duration (60–70 W) catheter ablation for atrial fibrillation: results of a large comparative analysis2022 · 28 citations
  4. 4Intracardiac pulsed field ablation: Proof of feasibility in a chronic porcine model2018 · 218 citations
  5. 5Effect of contact force on pulsed field ablation lesions in porcine cardiac tissue2023 · 77 citations