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October 7, 1999New England Journal of Medicine3,671 citationsOpen Access

Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

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ECEugenia E. CalleUniversidad Tecnica de Machala
Michael J. Thun
Michael J. ThunBrigham Young University
JPJennifer M. PetrelliAmerican Cancer Society

Key Points

  • To examine the association between body-mass index and risk of death from all causes, cardiovascular disease, cancer, and other conditions across diverse demographic groups.
  • Followed a prospective cohort of adult men and women across various age and racial categories.
  • Evaluated mortality risk across categories of moderate and severe overweight compared to standard reference ranges.
  • Risk of death from all causes, cardiovascular disease, cancer, and other diseases increases progressively across moderate and severe overweight ranges for both men and women in all age groups.
  • Mortality risk associated with elevated body-mass index is greater among white individuals than Black individuals.

Abstract

The risk of death from all causes, cardiovascular disease, cancer, or other diseases increases throughout the range of moderate and severe overweight for both men and women in all age groups. The risk associated with a high body-mass index is greater for whites than for blacks.

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Cite This Study

Calle et al. (1999) studied this question.

synapsesocial.com/papers/69d6a930a0177bf533ed87f2https://doi.org/10.1056/nejm199910073411501
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