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August 25, 2010New England Journal of Medicine3,563 citations

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

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KFKeith T. FlahertyIPIgor PuzanovKKKevin B. Kim

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Abstract

Treatment of metastatic melanoma with PLX4032 in patients with tumors that carry the V600E BRAF mutation resulted in complete or partial tumor regression in the majority of patients. (Funded by Plexxikon and Roche Pharmaceuticals.)

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Cite This Study

Flaherty et al. (2010) studied this question.

synapsesocial.com/papers/69d6bfdbfca0359822aa831ehttps://doi.org/10.1056/nejmoa1002011
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