PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
August 18, 2020Clinical Cancer Research277 citationsOpen Access

Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma

MMMark R. MiddletonCMCheryl McAlpineVWVictoria K. Woodcock

Key Points

Key points are not available for this paper at this time.

Abstract

These data suggest that redirecting T cells using a gp100-targeting TCR/anti-CD3 bispecific fusion protein may provide benefit to patients with metastatic melanoma. Furthermore, the activity observed in these two molecularly disparate melanoma classes hints at the broad therapeutic potential of tebentafusp.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Middleton et al. (2020) studied this question.

synapsesocial.com/papers/69d70857a0177bf533ed9946https://doi.org/10.1158/1078-0432.ccr-20-1247
Ask AI
Helpful
Bookmark
Share
View Full Paper