Does 18F-fluoride PET-CT identify subclinical bioprosthetic valve degeneration and predict subsequent valvular dysfunction in patients with bioprosthetic aortic valves?
18F-fluoride PET-CT shows major promise as a non-invasive imaging tool for the early diagnosis of bioprosthetic valve degeneration and surveillance of patients at risk for valve failure.
18F-fluoride PET-CT identifies subclinical bioprosthetic valve degeneration, providing powerful prediction of subsequent valvular dysfunction and highlighting patients at risk of valve failure. This technique holds major promise in the diagnosis of valvular degeneration and the surveillance of patients with bioprosthetic valves. (18F-Fluoride Assessment of Aortic Bioprosthesis Durability and Outcome 18F-FAABULOUS; NCT02304276).
Cartlidge et al. (2019) studied this question.