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December 14, 2022Frontiers in Medicine9 citationsOpen Access

Incidence, risk factors and clinical outcomes of septic acute renal injury in cancer patients with sepsis admitted to the ICU: A retrospective study

YYYong YangJDJun DongXCXiaojie Chen

Structured PICO

What are the risk factors for septic acute kidney injury and does it affect 28-day clinical outcomes in cancer patients with sepsis admitted to the ICU?

P
Population
Cancer patients with sepsis admitted to the ICU
I
Intervention
Septic acute kidney injury (AKI) as an exposure, and continuous renal replacement therapy (CRRT) as a treatment
C
Comparator
Patients without septic AKI
O
Outcome
Clinical outcomes within 28 days after ICU admission

In cancer patients with sepsis in the ICU, septic AKI is associated with worse 28-day outcomes, and CRRT does not significantly improve short-term prognosis.

Abstract

Lactate level, SOFA score and septic shock were closely related to the occurrence of septic AKI in the ICU. The clinical outcomes within 28 days after ICU admission of cancer patients with septic AKI were worse than those without septic AKI. The short-term outcome was worse in patients with septic AKI complicated with septic shock. CRRT does not have any significant effect on the short-term prognosis of cancer patients with septic AKI in the ICU.

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Cite This Study

Yang et al. (2022) studied this question.

synapsesocial.com/papers/69d735b73f2a6ac123b8a683https://doi.org/10.3389/fmed.2022.1015735
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