Does erythropoietin improve exercise capacity in patients with moderate to severe chronic heart failure?
Erythropoietin improves exercise capacity in patients with moderate to severe chronic heart failure by increasing hemoglobin concentration and oxygen delivery.
EPO significantly enhances exercise capacity in patients with CHF. One mechanism of improvement in VO2 is increased oxygen delivery from increased hemoglobin concentration.
Mancini et al. (Tue,) studied this question.