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March 14, 2016Journal of Clinical Oncology142 citationsOpen Access

Efficacy and Biomarker Study of Bevacizumab for Hearing Loss Resulting From Neurofibromatosis Type 2–Associated Vestibular Schwannomas

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JBJaishri O. BlakeleyJohns Hopkins UniversityXYXiaobu YeJohns Hopkins UniversityDDDan G. DudaCornell University

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Abstract

Bevacizumab treatment resulted in durable hearing response in 36% of patients with NF2 and confirmed progressive VS-associated hearing loss. Imaging and plasma biomarkers showed promising associations with response that should be validated in larger studies.

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Cite This Study

Blakeley et al. (2016) studied this question.

synapsesocial.com/papers/69d75be7f07a12db70b8ab71https://doi.org/10.1200/jco.2015.64.3817
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Also Consider

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  2. 2National Institutes of Health Consensus Development Conference Statement on Acoustic Neuroma, December 11-13, 19911994 · 81 citations
  3. 3Speech-Discrimination Scores Modeled as a Binomial Variable1978 · 543 citations
  4. 4Biomarkers of response and resistance to antiangiogenic therapy2009 · 575 citations
  5. 5Expression of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor in Sporadic Vestibular Schwannomas Correlates to Growth Characteristics2007 · 53 citations