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May 8, 2014Neurology209 citationsOpen Access

Initial cognitive decline is associated with cortical thinning in early Parkinson disease

JPJoana B. PereiraPSPer SvenningssonDWDaniel Weintraub

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Abstract

These findings confirm that MCI is associated with widespread cortical atrophy. In addition, they suggest that regional cortical thinning is already present at the time of diagnosis in patients with early, untreated PD who do not meet the criteria for MCI. Together, the results indicate that cortical thinning can serve as a marker for initial cognitive decline in early PD.

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Cite This Study

Pereira et al. (2014) studied this question.

synapsesocial.com/papers/69d75c90f182769aa8b8aaa1https://doi.org/10.1212/wnl.0000000000000483
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