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August 26, 2005Arteriosclerosis Thrombosis and Vascular Biology1,040 citationsOpen Access

A Paracrine Loop Between Adipocytes and Macrophages Aggravates Inflammatory Changes

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TSTakayoshi SuganamiJNJunko NishidaYOYoshihiro Ogawa

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Abstract

We postulate that a paracrine loop involving FFAs and TNF-alpha between adipocytes and macrophages establishes a vicious cycle that aggravates inflammatory changes in the adipose tissue.

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Suganami et al. (2005) studied this question.

synapsesocial.com/papers/69d75e4eb4cef8fedc48f9d4https://doi.org/10.1161/01.atv.0000183883.72263.13
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