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April 23, 2018JAMA Neurology402 citationsOpen Access

Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease

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IPInga PeterMDMarla DubinskySBSusan Bressman

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Abstract

A higher incidence of PD was observed among patients with IBD than among individuals without IBD. Early exposure to antiinflammatory anti-TNF therapy was associated with substantially reduced PD incidence. These findings support a role of systemic inflammation in the pathogenesis of both diseases. Further studies are required to determine whether anti-TNF treatment administered to high-risk individuals may mitigate PD risk.

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Peter et al. (2018) studied this question.

synapsesocial.com/papers/69d77bebaa68b335b4f31ae9https://doi.org/10.1001/jamaneurol.2018.0605
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