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February 17, 2016Clinical Chemistry223 citationsOpen Access

Increased Remnant Cholesterol Explains Part of Residual Risk of All-Cause Mortality in 5414 Patients with Ischemic Heart Disease

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AJAnne-Marie K JepsenALAnne LangstedAVAnette Varbo

Structured PICO

Are increased concentrations of remnant cholesterol associated with increased all-cause mortality in patients with ischemic heart disease?

P
Population
5414 patients with ischemic heart disease
I
Intervention
Increased concentrations of calculated and measured remnant cholesterol (exposure)
O
Outcome
All-cause mortalityhard clinical

Increased remnant cholesterol, rather than measured LDL cholesterol, explains part of the residual risk of all-cause mortality in patients with ischemic heart disease.

Abstract

Increased concentrations of both calculated and measured remnant cholesterol were associated with increased all-cause mortality in patients with ischemic heart disease, which was not the case for increased concentrations of measured LDL cholesterol. This suggests that increased concentrations of remnant cholesterol explain part of the residual risk of all-cause mortality in patients with ischemic heart disease.

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Cite This Study

Jepsen et al. (2016) studied this question.

synapsesocial.com/papers/69d7ba8a3b601d7be3ae2989https://doi.org/10.1373/clinchem.2015.253757
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