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July 18, 2008Journal of the American Chemical Society181 citations

Direct Acylation of Aryl Bromides with Aldehydes by Palladium Catalysis

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JRJiwu RuanOSOurida SaidiJIJonathan A. Iggo

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Abstract

A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis, affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner, and broadening the scope of metal-catalyzed coupling reactions.

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Cite This Study

Ruan et al. (2008) studied this question.

synapsesocial.com/papers/69d7bc386c394ad7d0bed8b4https://doi.org/10.1021/ja804351z
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