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November 18, 2014New England Journal of Medicine1,405 citationsOpen Access

HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

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ARAnand RohatgiAKAmit KheraJBJarett D. Berry

Key Points

  • To assess the relationship between HDL cholesterol efflux capacity, a measure of reverse cholesterol transport function, and the risk of incident cardiovascular events.
  • Measured cholesterol efflux capacity as a functional biomarker of reverse cholesterol transport.
  • Tracked incident cardiovascular events within a population-based cohort.
  • Cholesterol efflux capacity showed a significant inverse association with the incidence of cardiovascular events.

Abstract

Cholesterol efflux capacity, a new biomarker that characterizes a key step in reverse cholesterol transport, was inversely associated with the incidence of cardiovascular events in a population-based cohort. (Funded by the Donald W. Reynolds Foundation and others.).

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Cite This Study

Rohatgi et al. (2014) studied this question.

synapsesocial.com/papers/69d7c42005ee2ba81dbedc93https://doi.org/10.1056/nejmoa1409065
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