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September 21, 2004Annals of Internal Medicine1,672 citations

Meta-Analysis: Glycosylated Hemoglobin and Cardiovascular Disease in Diabetes Mellitus

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ESElizabeth SelvinSMSpyridon S MarinopoulosGBGail Berkenblit

Key Points

  • This analysis aims to evaluate the relationship between glycosylated hemoglobin levels and cardiovascular disease in people with diabetes mellitus.
  • Conducted a meta-analysis of observational studies and limited clinical trial data.
  • Focused on the association between chronic hyperglycemia and cardiovascular outcomes.
  • Findings indicate that chronic hyperglycemia correlates with higher cardiovascular disease risk.
  • Observational studies consistently support the link, despite limited clinical trial confirmation.

Abstract

Pending confirmation from large, ongoing clinical trials, this analysis shows that observational studies are consistent with limited clinical trial data and suggests that chronic hyperglycemia is associated with an increased risk for cardiovascular disease in persons with diabetes.

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Cite This Study

Selvin et al. (2004) studied this question.

synapsesocial.com/papers/69d7e89b319e71454dbedd1ahttps://doi.org/10.7326/0003-4819-141-6-200409210-00007
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