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March 12, 2008New England Journal of Medicine3,693 citationsOpen Access

Epigenetics in Cancer

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MEManel Esteller

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Abstract

Gene transcription can be activated or inhibited by a reversible modification of the gene; this modification is termed an epigenetic change. This account of epigenetics in cancer reviews the mechanisms and consequences of epigenetic changes in cancer cells and concludes with the implications of these changes for the diagnosis, prognosis, and treatment of cancer.

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Manel Esteller (2008) studied this question.

synapsesocial.com/papers/69d7e906319e71454dbedd49https://doi.org/10.1056/nejmra072067
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