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May 30, 2014SHILAP Revista de lepidopterología121 citationsOpen Access

Anti-Fibrotic Actions of Interleukin-10 against Hypertrophic Scarring by Activation of PI3K/AKT and STAT3 Signaling Pathways in Scar-Forming Fibroblasts

JSJihong ShiJLJun LiHGHao Guan

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Abstract

IL-10 apparently inhibits fibrosis by activating AKT and STAT3 phosphorylation downstream of the IL-10 receptor, and by facilitating crosstalk between the PI3K/AKT and STAT3 signal transduction pathways.

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Cite This Study

Shi et al. (2014) studied this question.

synapsesocial.com/papers/69d7ee6c5c3030ff03d18569https://doi.org/10.1371/journal.pone.0098228
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