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December 12, 2014Anesthesia & Analgesia227 citations

A Phase IIa, Randomized, Double-Blind Study of Remimazolam (CNS 7056) Versus Midazolam for Sedation in Upper Gastrointestinal Endoscopy

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KBKeith M. BorkettDRDennis RiffHSHoward I. Schwartz

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Abstract

This exploratory dose-finding study showed that a single administration of remimazolam (0.10-0.20 mg/kg) was capable of inducing rapid sedation with a quick recovery profile in patients undergoing a diagnostic upper gastrointestinal endoscopy. The safety profile was favorable and appeared to be similar to that of midazolam, warranting further development of this short-acting compound.

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Cite This Study

Borkett et al. (2014) studied this question.

synapsesocial.com/papers/69d83a988c03fbaff8bee4c6https://doi.org/10.1213/ane.0000000000000548
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