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November 1, 1998Journal of Hypertension286 citations

Heart rate as marker of sympathetic activity

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GGGuido GrassiUniversity of Milano-BicoccaSVS. VailatiZambon (Italy)GBGiovanni BertinieriOspedale degli Infermi

Structured PICO

Is supine heart rate a reliable marker of sympathetic tone in the general population and patients with cardiovascular disease?

P
Population
General population and patients with cardiovascular diseases (including essential hypertension, obesity, and heart failure)
I
Intervention
Supine heart rate measurement
O
Outcome
Sympathetic tonesurrogate

Supine heart rate has limited utility as a marker of sympathetic tone, particularly in patients with essential hypertension.

Limitations

  • Limited value as a marker, particularly in essential hypertension

Abstract

These data suggest that the supine heart rate can be regarded as a marker of intersubject differences in sympathetic tone, and that this is the case both in the general population and in those with cardiovascular diseases. Its value for this purpose is limited, however, and the limitations may be more evident in essential hypertension than in conditions such as obesity and heart failure.

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Cite This Study

Grassi et al. (1998) studied this question.

synapsesocial.com/papers/69d8775fd56ca42147d18959https://doi.org/10.1097/00004872-199816110-00010
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Dissociation Between Muscle and Skin Sympathetic Nerve Activity in Essential Hypertension, Obesity, and Congestive Heart Failure1998 · 257 citations
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  5. 5Studies of the mechanisms underlying impairment of beta-adrenoceptor-mediated effects in human hypertension.1983 · 43 citations