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August 15, 2018New England Journal of Medicine941 citations

Clinical Course and Management of Hypertrophic Cardiomyopathy

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BMBarry J. Maron

Key Points

  • To review the epidemiology, clinical presentation, and therapeutic strategies in the management of hypertrophic cardiomyopathy.
  • Evaluation of clinical course data and disease prevalence across general populations.

Structured PICO

Do pharmacologic, electrical, and surgical interventions reduce mortality in patients with Hypertrophic Cardiomyopathy?

P
Population
Persons with Hypertrophic Cardiomyopathy (HCM)
I
Intervention
Pharmacologic, electrical, and surgical interventions
O
Outcome
Mortalityhard clinical

Modern management strategies including pharmacologic, electrical, and surgical interventions have successfully reduced HCM mortality to 0.5% per year.

Abstract

HCM is the most common genetic disorder of the heart, with 1 case per 200 to 500 persons, and often remains clinically silent. HCM is the most common cause of sudden death in athletes, but pharmacologic, electrical, and surgical interventions have reduced mortality to 0.5% per year.

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Cite This Study

Barry J. Maron (2018) studied this question.

synapsesocial.com/papers/69d88ff78cb8f39931ae33e2https://doi.org/10.1056/nejmra1710575
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